Emergence of Malignant Lesions Within an Adenomatous Hyperplastic Nodule in a Cirrhotic Liver

摘要: Abstract Five cases of an adenomatous hyperplastic nodule or a similar lesion resected from cirrhotic liver in which early malignant foci were seen as small nodule-in-nodule lesions are described. These detected by imaging diagnosis patients with nonalcoholic cirrhosis, mostly during routine clinical follow-up. In 2 patients, recurrence hepatocellular carcinoma occurred 11 mo and 15 postresection. Thus, these nodule-innodule seem to represent stage hepatocarcinogenesis humans. Japan Southeast Asia, whom is endemic, that occurs livers may be preneoplastic already committed transformation.