作者: Walid Ayoub
DOI: 10.2147/VAAT.S4712
关键词:
摘要: Treatment of chronic hepatitis B (CHB) continues to evolve. Over the last decade, progressively lower levels serum HBV DNA have been used as a threshold for treatment. A high degree antiviral potency and low rate resistance are two most important factors in choice an agent therapy CHB. Achieving rapid viral suppression is also key factor choosing first line therapy. Swift potent decreases risk hepatic decompensation, development hepatocellular carcinoma subsequent need liver transplantation. Currently, entecavir tenofovir nucleoside nucleotide analogs with lowest treatment-naive patients. This review will evaluate safety efficacy use disoproxil fumarate, newest agent, treatment patients