摘要: Bacterial, fungal, viral, and parasitic pathogens all cause systemic infection can spread to the eye. Dissemination of via bloodstream lead direct involvement Visual loss is common in bacterial or fungal endophthalmitis, toxoplasmosis a major ocular morbidity poor vision after congenital acquired infection. Some infections intraocular damage by indirect mechanisms (eg, HIV-mediated immunosuppression), leading opportunistic such as cytomegalovirus infection, periocular nerve due leprosy, hypersensitivity reactions tuberculosis. Eye symptoms might indicate outcome an underlying development retinal ischaemia severe malaria, which associated with prognosis. Successful for patients depends on close collaboration between clinicians identifying treating disease, specialist ophthalmic review, interventional skills (when needed).