Coffee prevents proximal colorectal adenomas in Japanese men

摘要: This prospective cohort study aimed to show that coffee prevents the recurrence of colorectal tumors (adenomas, precursors cancer, and early-stage cancers) as well cancer. The present included 307 patients who participated in a clinical required endoscopy remove tumor. amount consumed by at inclusion frequency tumors, detected colonoscopy over subsequent 4 years, were assessed. Coffee consumption was determined using diet survey 3-consecutive-day food records. risk tumor significantly lower (odds ratio=0.21; 95% confidence interval, 0.06-0.74) more than three cups per day compared with those no coffee. No correlation observed between examined factors, including green tea black intake caffeine consumed. In subanalysis divided location within colorectum, odds ratio proximal colon showed tendency toward reduction increased; however, increased distal colon. We high reduced overall occurrence affected