Reprint of "Learning to breathe? Feedforward regulation of the inspiratory motor drive".

摘要: Abstract Claims have been made that breathing is in part controlled by feedforward regulation. In a classical conditioning paradigm, we investigated anticipatory increases the inspiratory motor drive as measured occlusion pressure (P100). an acquisition phase, experimental group (N = 13) received low-intensity resistive load (5 cmH2O/l/s) for three consecutive inspirations Conditioned Stimulus (CS), preceding of stronger intensity (20 cmH2O/l/s) subsequent unconditioned stimulus (US). The control (N = 11) six inspirations. post-acquisition phase both groups Responses to CS-load only differed between during first trials and strong increase P100 US-loads was observed, which habituated across experiment. Our results suggest disruption caused adding low moderate loads short-lasting drive.