HIV Preexposure Prophylaxis and Condomless Sex: Disentangling Personal Values From Public Health Priorities

作者: Sarah K. Calabrese , Kristen Underhill , Kenneth H. Mayer

DOI: 10.2105/AJPH.2017.303966

关键词:

摘要: Daily HIV preexposure prophylaxis (PrEP) is an effective form of protection that remains unknown and inaccessible for many people in the United States despite receiving federal approval over five years ago.PrEP supported by public health community, but forgoing condoms while taking PrEP has proven controversial; this controversy may be contributing to lag uptake. We argue limiting access based on anticipated or actual sexual behavior contradicts goals research practice not scientifically justified.As evidence effectiveness novel forms biomedical emerges, professionals need accept new definitions “protected sex” ensure their personal values do override empirical when determining priorities.

参考文章(19)
Sheena McCormack, David T Dunn, Monica Desai, David I Dolling, Mitzy Gafos, Richard Gilson, Ann K Sullivan, Amanda Clarke, Iain Reeves, Gabriel Schembri, Nicola Mackie, Christine Bowman, Charles J Lacey, Vanessa Apea, Michael Brady, Julie Fox, Stephen Taylor, Simone Antonucci, Saye H Khoo, James Rooney, Anthony Nardone, Martin Fisher, Alan McOwan, Andrew N Phillips, Anne M Johnson, Brian Gazzard, Owen N Gill, Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial The Lancet. ,vol. 387, pp. 53- 60 ,(2016) , 10.1016/S0140-6736(15)00056-2
Richard Crosby, Stephanie Sanders, William L Yarber, Cynthia A Graham, Condom-use errors and problems: A neglected aspect of studies assessing condom effectiveness American Journal of Preventive Medicine. ,vol. 24, pp. 367- 370 ,(2003) , 10.1016/S0749-3797(03)00015-1
Jonathan E. Volk, Julia L. Marcus, Tony Phengrasamy, Derek Blechinger, Dong Phuong Nguyen, Stephen Follansbee, C. Bradley Hare, No New HIV Infections With Increasing Use of HIV Preexposure Prophylaxis in a Clinical Practice Setting Clinical Infectious Diseases. ,vol. 61, pp. 1601- 1603 ,(2015) , 10.1093/CID/CIV778
Sarah K. Calabrese, Valerie A. Earnshaw, Kristen Underhill, Nathan B. Hansen, John F. Dovidio, The impact of patient race on clinical decisions related to prescribing HIV pre-exposure prophylaxis (PrEP): assumptions about sexual risk compensation and implications for access. Aids and Behavior. ,vol. 18, pp. 226- 240 ,(2014) , 10.1007/S10461-013-0675-X
Nancy E. Kass, An Ethics Framework for Public Health American Journal of Public Health. ,vol. 91, pp. 1776- 1782 ,(2001) , 10.2105/AJPH.91.11.1776
Albert Y. Liu, Stephanie E. Cohen, Eric Vittinghoff, Peter L. Anderson, Susanne Doblecki-Lewis, Oliver Bacon, Wairimu Chege, Brian S. Postle, Tim Matheson, K. Rivet Amico, Teri Liegler, M. Keith Rawlings, Nikole Trainor, Robert Wilder Blue, Yannine Estrada, Megan E. Coleman, Gabriel Cardenas, Daniel J. Feaster, Robert Grant, Susan S. Philip, Richard Elion, Susan Buchbinder, Michael A. Kolber, Preexposure Prophylaxis for HIV Infection Integrated With Municipal- and Community-Based Sexual Health Services JAMA Internal Medicine. ,vol. 176, pp. 75- 84 ,(2016) , 10.1001/JAMAINTERNMED.2015.4683
Virginia A. Fonner, Sarah L. Dalglish, Caitlin E. Kennedy, Rachel Baggaley, Kevin R. O’Reilly, Florence M. Koechlin, Michelle Rodolph, Ioannis Hodges-Mameletzis, Robert M. Grant, Effectiveness and safety of oral HIV preexposure prophylaxis for all populations. AIDS. ,vol. 30, pp. 1973- 1983 ,(2016) , 10.1097/QAD.0000000000001145