INDUCTION OF MUTATIONS BY γ-RAYS IN PREGONIAL GERM CELLS OF ZEBRAFISH EMBRYOS
作者： Charline Walker , George Streisinger
DOI: 10.1093/GENETICS/103.1.125
关键词:
摘要: Specific locus (gol-1) germ line mutations are induced by gamma-rays with high frequencies (about 10(-5) r( -1)) during cleavage divisions in zebrafish. Mutant clone sizes range from 3 to 50% of the total number cells, a mean about 10%, when embryos exposed between 16 and 10(3) cell stages. About five pregonial cells calculated be present period.
genetics.org参考文章(5)
A. G. Searle, Evidence from mutable genes concerning the origin of the germ line. Basic life sciences. ,vol. 12, pp. 209- 224 ,(1978) , 10.1007/978-1-4684-3390-6_16
E. Himoe, Helen Unger Meyer, G. Daniel, S. Abrahamson, Further evidence demonstrating germinal selection in early premeiotic germ cells of Drosophila males. Genetics. ,vol. 54, pp. 687- 697 ,(1966) , 10.1093/GENETICS/54.2.687
George Streisinger, Charline Walker, Nancy Dower, Donna Knauber, Fred Singer, Production of clones of homozygous diploid zebra fish ( Brachydanio rerio ) Nature. ,vol. 291, pp. 293- 296 ,(1981) , 10.1038/291293A0
Liane B. Russell, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. ,vol. 11, pp. 107- 123 ,(1971) , 10.1016/0027-5107(71)90036-4
Sankar Chakrabarti, George Streisinger, Fred Singer, Charline Walker, FREQUENCY OF γ-RAY INDUCED SPECIFIC LOCUS AND RECESSIVE LETHAL MUTATIONS IN MATURE GERM CELLS OF THE ZEBRAFISH, BRACHYDANIO RERIO Genetics. ,vol. 103, pp. 109- 123 ,(1983) , 10.1093/GENETICS/103.1.109