Clinical and pathologic parameters predicting recurrence of facial basal cell carcinoma: a retrospective audit in an advanced care center

作者: Matthias Troeltzsch , Florian A. Probst , Thomas Knösel , Gerson Mast , Michael Ehrenfeld

DOI: 10.1111/IJD.13341

关键词:

摘要: Objectives This study was designed to investigate the associations between clinical, pathologic, and therapeutic parameters of facial basal cell carcinoma (BCC) recurrence rates in patients treated at an advanced care center. Methods A retrospective cohort performed. Patients who presented center within a 6-year period with BCC received surgical treatment were included for further review according predefined inclusion criteria. The predictor variable defined as “negative-margin (R0) resection after first surgery”. primary outcome “BCC recurrence”. Descriptive inferential statistics computed. significance level set P ≤ 0.05. Results A total 71 (29 female, 42 male; average age: 71.76 years) found meet all All BCCs had been referred, 50.7% submitted previous surgery. mean ± standard deviation tumor diameter 2.3 1.8 cm. Recurrence observed 11 (15.5%). Large diameters, increased patient age, failure achieve R0 appointment significantly rates. Conclusions Complete excision is pivotal reducing likelihood recurrence. influence anatomic location on may be limited.

参考文章(37)
Mizuki GOTO, Yoshitaka KAI, Shoko ARAKAWA, Masaki OISHI, Kazushi ISHIKAWA, Saburou ANZAI, Yutaka HATANO, Osamu OKAMOTO, Kazumoto KATAGIRI, Sakuhei FUJIWARA, Fumiaki SHIMIZU, Aiko KATO, Hiromi SHIBUYA, Nobuoki ESHIMA, Hiroto TERASHI, Analysis of 256 cases of basal cell carcinoma after either one‐step or two‐step surgery in a Japanese institution Journal of Dermatology. ,vol. 39, pp. 68- 71 ,(2012) , 10.1111/J.1346-8138.2011.01306.X
Roberto Betti, Carlo Crosti, Simona Ghiozzi, Amilcare Cerri, Laura Moneghini, Silvano Menni, Basosquamous cell carcinoma: a survey of 76 patients and a comparative analysis of basal cell carcinomas and squamous cell carcinomas European Journal of Dermatology. ,vol. 23, pp. 83- 86 ,(2013) , 10.1684/EJD.2012.1890
Stanley J Miller, Murad Alam, James Andersen, Daniel Berg, Christopher K Bichakjian, Glen Bowen, Richard T Cheney, L Frank Glass, Roy C Grekin, Anne Kessinger, Nancy Y Lee, Nanette Liegeois, Daniel D Lydiatt, Jeff Michalski, William H Morrison, Kishwer S Nehal, Kelly C Nelson, Paul Nghiem, Thomas Olencki, Clifford S Perlis, E William Rosenberg, Ashok R Shaha, Marshall M Urist, Linda C Wang, John A Zic, None, Basal cell and squamous cell skin cancers. Journal of The National Comprehensive Cancer Network. ,vol. 8, pp. 836- 864 ,(2010) , 10.6004/JNCCN.2010.0062
A.A. Khan, M. Potter, J.J. Cubitt, B.J. Khoda, J. Smith, E.H. Wright, G. Scerri, A. Crick, O.C. Cassell, P.G. Budny, Guidelines for the excision of cutaneous squamous cell cancers in the United Kingdom: The best cut is the deepest Journal of Plastic Reconstructive and Aesthetic Surgery. ,vol. 66, pp. 467- 471 ,(2013) , 10.1016/J.BJPS.2012.12.016
Gregor F. Raschke, Ulrich M. Rieger, Rolf-Dieter Bader, Arndt Guentsch, Oliver Schaefer, Stefan Elstner, Stefan Schultze-Mosgau, Cheek rotation flap reconstruction—an anthropometric appraisal of surgical outcomes Clinical Oral Investigations. ,vol. 18, pp. 1251- 1257 ,(2014) , 10.1007/S00784-013-1075-3
Prem Kumar, Stewart Watson, Anne N. Brain, Saumitra S. Banerjee, Peter J. Davenport, David L. Bisset, Lorna J. McWilliam, Incomplete excision of basal cell carcinoma: a prospective multicentre audit. British Journal of Plastic Surgery. ,vol. 55, pp. 616- 622 ,(2002) , 10.1054/BJPS.2002.3948
June K. Robinson, Susan G. Fisher, Recurrent Basal Cell Carcinoma After Incomplete Resection Archives of Dermatology. ,vol. 136, pp. 1318- 1324 ,(2000) , 10.1001/ARCHDERM.136.11.1318
B. Niederhagen, J.-J.von Lindern, S. Bergé, T. Appel, R.H. Reich, E. Krüger, Staged operations for basal cell carcinoma of the face British Journal of Oral & Maxillofacial Surgery. ,vol. 38, pp. 477- 479 ,(2000) , 10.1054/BJOM.2000.0322
Kong-Bing Tan, Sze-Hwa Tan, Derrick Chen-Wee Aw, Huma Jaffar, Thiam-Chye Lim, Shu-Jin Lee, Yoke-Sun Lee, Simulators of Squamous Cell Carcinoma of the Skin: Diagnostic Challenges on Small Biopsies and Clinicopathological Correlation Journal of skin cancer. ,vol. 2013, pp. 752864- 752864 ,(2013) , 10.1155/2013/752864