Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation.
作者： Yi Luo , Brad Bolon , Steve Kahn , Brian D. Bennett , Safura Babu-Khan
DOI: 10.1038/85059
关键词:
摘要: Mice deficient in BACE1 (beta-site APP cleaving enzyme 1) are healthy, fertile and appear normal in gross anatomy, tissue histology, hematology and clinical chemistry. BACE1−/− mice …
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