Untangling hybrid phylogenetic signals: horizontal gene transfer and artifacts of phylogenetic reconstruction.

摘要: Phylogenomic methods can be used to investigate the tangled evolutionary relationships among genomes. Building ‘all trees of all genes’ potentially identify common pathways horizontal gene transfer (HGT) taxa at varying levels phylogenetic depth. Phylogenetic affinities aggregated and merged with information about genetic linkage biochemical function examine hypotheses adaptive evolution via HGT. Additionally, use many data sets increases power statistical tests for artifacts. However, large-scale analyses pose several challenges, including necessary abandonment manual validation techniques, need translate inferred discordance into HGT events, challenges involved in aggregating results from search-based inference methods. In this chapter we describe a tree search procedure recover most parsimonious HGT, some assumptions that are made by method.