Prediction of drug transport through the blood-brain barrier in vivo: a comparison between two in vitro cell models.
作者： Stefan Lundquist , Mila Renftel , Julien Brillault , Laurence Fenart , Roméo Cecchelli
关键词:
摘要: Purpose. Studies were conducted to evaluate whether the use of an in vitro model blood-brain barrier (BBB) resulted more accurate predictions vivo transport compounds compared a human intestinal cell line (Caco-2).
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