Attributable Outcomes of Endemic Clostridium difficile–associated Disease in Nonsurgical Patients

摘要: Data are limited on the attributable outcomes of Clostridium difficile-associated disease (CDAD), particularly in CDAD-endemic settings. We conducted a retrospective cohort study nonsurgical inpatients admitted for >/=48 hours 2003 (N = 18,050). The adjusted hazard ratios readmission (hazard ratio 2.19, 95% confidence interval [CI] 1.87-2.55) and deaths within 180 days 1.23, CI 1.03-1.46) were significantly different among CDAD case-patients noncase patients. In propensity score matched-pairs analysis that used nested subset 706), length stay to was 2.8 days, at 19.3%, death 5.7%. patients more likely than controls be discharged long-term-care facility or outside hospital. Even nonoutbreak setting, had statistically significant negative impact patient illness death, persisted beyond hospital discharge.