Process of preparing esters and ethers of probucol and derivatives thereof

摘要: A probucol or a derivative can be efficiently converted to monoester monoether of by reacting the free hydroxyl-containing thereof (by which is meant compound with at least one substituent that different from on parent molecule but maintains two hydroxyl groups) Grignard reagent lithium produces magnesium bromide salt derivative. The anion then reacted an ester ether forming compound.