Resistance to HIV-1 infection. Multicenter AIDS Cohort Study.

摘要: Men from the Multicenter AIDS Cohort Study were classified as "susceptible" and "resistant" to HIV infection. Resistant men still antibody negative in 1993 estimated have had > 45 different anal intercourse partners (median, 92; range, 46-504) 2.5 years before visit 2 (1985). Susceptible seroconverters who < 13 4; 0-12). Leukocyte groups compared between two of men. Values excluded for 12 months first antibody-positive susceptible White blood cells, polymorphonuclear neutrophils, total lymphocyte count, CD8+ percentage number, CD3+ CD4+ number higher resistant Logistic regression analyses used develop 50 bivariate models. Higher levels neutrophils cells included four six best-fitting models, suggesting that each is associated with resistance HIV-1 These results support hypothesis may modulate outcome exposure.