Multifold Fluorescence Enhancement in Nanoscopic Fluorophore–Clay Hybrids in Transparent Aqueous Media
作者： Tom Felbeck , Simon Mundinger , Marina M. Lezhnina , Mark Staniford , Ute Resch-Genger
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摘要: Valuable emissive properties of organic fluorophores have become indispensable analytical tools in biophotonics, but frequently suffer from low solubilities and radiationless deactivation aqueous media, that is, biological ambience as well. In this report, nanoscaled dye-clay hybrids based on laponite, Na0.7 {(Li0.3 Mg5.5 )[Si8 O20 (OH)4 ]}, are taken advantage to solubilize neutral dyes, which natively not encountered water. Previously reported efficiency solubility bottlenecks such can a large extent be overcome by comparably simple chemical measures, demonstrated here for two prominent examples, the fluorescent dyes Nile Red Coumarin 153. On controlled co-adsorption small bifunctional quaternary ammonium ions (Me3 N(+) C2 H5 OH Me3 NH2 ) we observed an outright boost order magnitude, 30-fold brightness gain. Even at higher concentrations, transparency stability hybrid dispersions retained, rendering them useful employment optically functional nanoparticles bioassays beyond.
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