Effects of Green Tea Extract on Gene Expression in Human Hepatoma (HepG2) and Tongue Carcinoma (Cal-27) Cells
作者： Gregory M. Raner
DOI: 10.1016/B978-0-12-384937-3.00077-X
关键词:
摘要: Some of the beneficial health effects green tea extract can be traced to ability certain constituents in regulate gene expression. For example, and major catechins have been shown induce a variety products related anti-oxidant or other protective functions. The full range genes that are activated by this pathway is still being explored, however, molecular mechanisms involved reasonably well characterized. In addition genes, number apoptosis also respond GTE, through both induction repression. It likely anti-proliferative/anti-cancer GTE may expressed, part, via mechanism. Finally, drug metabolism, particular, cytochrome P450 enzymes, regulated which implications for development chemoprentive strategies using GTE.
sci-hub.st 参考文章(47)
Y Li, A.K. Jaiswal, Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element. Journal of Biological Chemistry. ,vol. 267, pp. 15097- 15104 ,(1992) , 10.1016/S0021-9258(18)42151-5
Jeffrey H. Weisburg, Danielle B. Weissman, Tannaz Sedaghat, Harvey Babich, In vitro Cytotoxicity of Epigallocatechin Gallate and Tea Extracts to Cancerous and Normal Cells from the Human Oral Cavity Pharmacology and Toxicology. ,vol. 95, pp. 191- 200 ,(2004) , 10.1111/J.1742-7843.2004.PTO_950407.X
Brian J. Philips, Christian H. Coyle, Shelby N. Morrisroe, Michael B. Chancellor, Naoki Yoshimura, Induction of apoptosis in human bladder cancer cells by green tea catechins Biomedical Research-tokyo. ,vol. 30, pp. 207- 215 ,(2009) , 10.2220/BIOMEDRES.30.207
Chi Chen, Rong Yu, Edward D. Owuor, A. -N. Tony Kong, Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death. Archives of Pharmacal Research. ,vol. 23, pp. 605- 612 ,(2000) , 10.1007/BF02975249
Hirak Kumar Barman, Yasunari Takami, Tatsuya Ono, Hitoshi Nishijima, Fumiyuki Sanematsu, Kei-ichi Shibahara, Tatsuo Nakayama, Histone acetyltransferase 1 is dispensable for replication-coupled chromatin assembly but contributes to recover DNA damages created following replication blockage in vertebrate cells Biochemical and Biophysical Research Communications. ,vol. 345, pp. 1547- 1557 ,(2006) , 10.1016/J.BBRC.2006.05.079
Oliver Eickelberg, Thomas Herdegen, Christian Trautwein, Kaimin Cha, Yuet Wai Kan, Thomas Pufe, Christoph Jan Wruck, Konrad Streetz, Goran Pavic, Mario E. Götz, Mersedeh Tohidnezhad, Lars-Ove Brandenburg, Deike Varoga, Nrf2 Induces Interleukin-6 (IL-6) Expression via an Antioxidant Response Element within the IL-6 Promoter Journal of Biological Chemistry. ,vol. 286, pp. 4493- 4499 ,(2011) , 10.1074/JBC.M110.162008
Christine M Palermo, Claire A Westlake, Thomas A Gasiewicz, None, Epigallocatechin gallate inhibits aryl hydrocarbon receptor gene transcription through an indirect mechanism involving binding to a 90 kDa heat shock protein. Biochemistry. ,vol. 44, pp. 5041- 5052 ,(2005) , 10.1021/BI047433P
Fen-Pi Chou, Yu-Chuan Chu, Jeng-Dong Hsu, Huei-Ching Chiang, Chau-Jong Wang, Specific induction of glutathione S-transferase GSTM2 subunit expression by epigallocatechin gallate in rat liver Biochemical Pharmacology. ,vol. 60, pp. 643- 650 ,(2000) , 10.1016/S0006-2952(00)00363-4
Bernhard Suter, Oxana Pogoutse, Xinghua Guo, Nevan Krogan, Peter Lewis, Jack F Greenblatt, Jasper Rine, Andrew Emili, Association with the origin recognition complex suggests a novel role for histone acetyltransferase Hat1p/Hat2p. BMC Biology. ,vol. 5, pp. 38- 38 ,(2007) , 10.1186/1741-7007-5-38
C. M. Palermo, J. I. Martin Hernando, S. D. Dertinger, A. S. Kende, T. A. Gasiewicz, Identification of potential aryl hydrocarbon receptor antagonists in green tea. Chemical Research in Toxicology. ,vol. 16, pp. 865- 872 ,(2003) , 10.1021/TX025672C