Transcription and Translation

摘要: Regulation of the transcription and translation mechanisms Helicobacter pylori is presumed to be similar those well-studied Escherichia coli, because both are gram-negative bacteria. Complete DNA sequencing genomes two different strains H. has allowed application powerful sequence homology searches assign putative functions various open reading frames (ORFs), leading hypotheses regarding transcriptional translational processes in genomes. This chapter focuses on experimental results dealing with obtained past few years. DNA-dependent RNA polymerase mediates synthesis from a template. The discovery that undergoes spontaneous autolysis toward end log-phase growth conversion bacteria into coccoid forms consistent these explanations. lack an identifiable ortholog rpoH been interpreted as suggesting may respond stress differently than other promoters classified by sigma factors involved (or involved) direct their transcription, i.e., σ70-dependent, σ54-dependent, σ28-dependent promoters. apparatus required for expression genetic information encoded cells. Components include ribosomes, tRNA, mRNA, numerous ligands, ions, nucleotides, several proteins, including tRNA-modifying enzymes, aminoacyl- tRNA synthetases, proteins transiently associated ribosomes. genome unique absence asparaginyl-tRNA synthetase gene. sequence-similarity comparisons