Population-based HIV-1 incidence in France, 2003–08: a modelling analysis
作者： Stéphane Le Vu , Yann Le Strat , Francis Barin , Josiane Pillonel , Françoise Cazein
DOI: 10.1016/S1473-3099(10)70167-5
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摘要: Summary Background Routine national incidence testing with enzyme immunoassay for recent HIV-1 infections (EIA-RI) has been done in France since January, 2003. From the reported number of HIV diagnosed as recent, and accounting patterns under-reporting, we aimed to estimate infection 2003–08. Methods We analysed reports from French National Institute Public Health Surveillance patients who were newly between 2003, December, 2008. Missing data imputed multiple imputation. Patients classified non-recent or on basis an EIA-RI test, which was calibrated serial measurements seroconverters ANRS-PRIMO cohort. used adapted stratified extrapolation approach calculate new men have sex (MSM), injecting drug users (IDUs), heterosexual women by nationality. Population sizes obtained census behavioural studies. Findings After there 6480 (95% CI 6190–6780) diagnoses that 6940 (6200–7690) 2008, suggesting 17 per 100 000 person-years. In 3550 (3040–4050) heterosexuals (incidence 9 person-years), 3320 (2830–3810) MSM 1006 70 (0–190) IDUs 86 person-years). Overall decreased 2003 2008 (p Interpretation France, transmission disproportionately affects certain risk groups seems be out control population. Incidence should tracked monitor dynamics various population help target assess prevention strategies. Funding (InVS) Agency Research AIDS Viral Hepatitis (ANRS).
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