Central Neck Dissection for Papillary Thyroid Cancer

作者: Michael A. Rosenbaum , Christopher R. McHenry

DOI: 10.1001/ARCHOTO.2009.158

关键词:

摘要: Objective To examine the role of central neck dissection (CND) in patients with papillary thyroid cancer (PTC). Design Retrospective analysis treated for PTC between 1993 and 2008. Setting Academic institution. Patients All diagnosed who underwent surgical therapy at our Main Outcome Measures Recurrence, hypocalcemia, hypoparathyroidism, recurrent laryngeal nerve (RLN) injury. Results A total 136 were PTC, 26 whom excluded because their initial resection was performed another Of 110 therapy, CND 22 (20%), 18 4 without enlarged nodes time surgery. mean (SD) 11 (4) lymph removed, node metastases identified 17 (77%). One patient developed a recurrence lateral 15 months' follow-up. Eighty-eight had no abnormal did not undergo CND, 2 (2%) ( P  = .49) 14 years' Permanent RLN injury occurred 1 (1%). Transient hypocalcemia 19 (86%) compared 54 (61%)  = .01). hypoparathyroidism (5%). Conclusion After thyroidectomy is uncommon, but more common, raising questions about use routine PTC.

参考文章(26)
Brian M. Sadowski, Samuel K. Snyder, Terry C. Lairmore, Routine bilateral central lymph node clearance for papillary thyroid cancer. Surgery. ,vol. 146, pp. 696- 705 ,(2009) , 10.1016/J.SURG.2009.06.046
Kylie L. Snook, Peter L. H. Stalberg, Stan B. Sidhu, Mark S. Sywak, Pamela Edhouse, Leigh Delbridge, Recurrence after Total Thyroidectomy for Benign Multinodular Goiter World Journal of Surgery. ,vol. 31, pp. 593- 598 ,(2007) , 10.1007/S00268-006-0135-0
Jong-Lyel Roh, Jae-Yong Park, Jin-Man Kim, Chang-Jun Song, Use of preoperative ultrasonography as guidance for neck dissection in patients with papillary thyroid carcinoma. Journal of Surgical Oncology. ,vol. 99, pp. 28- 31 ,(2009) , 10.1002/JSO.21164
Sameer William Qubain, Shizuo Nakano, Masamichi Baba, Sonshin Takao, Takashi Aikou, Distribution of lymph node micrometastasis in pN0 well-differentiated thyroid carcinoma. Surgery. ,vol. 131, pp. 249- 256 ,(2002) , 10.1067/MSY.2002.120657
Lars-Erik Tisell, Bengt Nilsson, Johan Mölne, Göran Hansson, Martha Fjälling, Svante Jansson, Urban Wingren, Improved survival of patients with papillary thyroid cancer after surgical microdissection. World Journal of Surgery. ,vol. 20, pp. 854- 859 ,(1996) , 10.1007/S002689900130
Georg F. W. Scheumann, Oliver Gimm, Gerd Wegener, H. Hundeshagen, Henning Dralle, Prognostic significance and surgical management of locoregional lymph node metastases in papillary thyroid cancer World Journal of Surgery. ,vol. 18, pp. 559- 568 ,(1994) , 10.1007/BF00353765
Yasuhiro Ito, Chisato Tomoda, Takashi Uruno, Yuuki Takamura, Akihiro Miya, Kaoru Kobayashi, Fumio Matsuzuka, Kanji Kuma, Akira Miyauchi, Clinical significance of metastasis to the central compartment from papillary microcarcinoma of the thyroid. World Journal of Surgery. ,vol. 30, pp. 91- 99 ,(2006) , 10.1007/S00268-005-0113-Y
Mark Sywak, Lachlan Cornford, Paul Roach, Peter Stalberg, Stan Sidhu, Leigh Delbridge, Routine ipsilateral level VI lymphadenectomy reduces postoperative thyroglobulin levels in papillary thyroid cancer. Surgery. ,vol. 140, pp. 1000- 1007 ,(2006) , 10.1016/J.SURG.2006.08.001