Pathogenesis of Acute Coronary Syndromes

摘要: Experimental models of atherogenesis have provided a growing body information about molecular mechanisms plaque growth; however, transition from coronary stability to instability is less well understood due the lack animal reflective human disease. The abrupt clinical presentation acute syndromes gives strong signal discontinuity in natural history atherothrombosis. causes such are complex, probably multiple, and still largely unknown. A better knowledge might allow identification new therapeutic targets aimed at preservation those subjects whom primary prevention fails prevent growth. goal this review was propose pathogenetic classification that help search diagnostic algorithms targets.