Is There a Health Benefit of Reduced Tobacco Consumption? A Systematic Review

摘要: This review presents the available evidence on health effects of reduced smoking. Smoking reduction was defined as daily intake tobacco without quitting. Only published papers were reviewed. Case reports and studies a thorough definition smoking or outcome excluded. We searched in personal databases, BioMail Medline Search, Medline, Cochrane Database Systematic Reviews, EMBASE. followed QUORUM standards for systematic reviews, both authors read discussed all publications. A total 25 (31 publications) identified: 8 articles reported cardiovascular system; 11 airways; 7 carcinogens, DNA damage, lung cancer; 3 birth weight; 4 other effects. Some assessed more than one outcome. In most studies, less 50% baseline consumption. Most small, with populations selected short follow-up periods. The limited data suggest that substantial improves several risk factors respiratory symptoms. addition, is associated 25% decline biomarkers incidence cancer mostly nonsignificant, increase weight. There seem to be no beneficial function. mortality too draw conclusions. seems have small benefit, but are needed determine long-term reduction.