Autonomous cage-side system for remote training of non-human primates.

摘要: Abstract Background Training non-human primates (NHPs) for translational medical experimentation is an essential yet time consuming process. To increase training efficiency, some systems have been designed NHPs to use at their home cages. Several autonomous cage-side tablet-based proposed, but none of these allow remote monitoring and task modification while also being wireless, low-cost, light weight, portable. New method Here we present ACTS: Autonomous Cage-side System which meets all criteria. ACTS consists 1) a touchscreen tablet speaker attached the subject’s cage, 2) inexpensive reward system made from slightly modified fish feeder, 3), laptop operating wirelessly remotely via router. Results We were able test train two macaques in Remote access enabled us control up 90 m, through 3 walls, floor building. The device compatible with different pellet sizes could run about hours ∼4 mm size. animals generalize when transferred traditional experimental rig. Comparison existing methods low cost modest skill required build implement lowers barrier NHP researchers caregivers deploy autonomous, controlled systems. Conclusion can be used wireless prepared experimentation.