Influence of dietary calcium and vitamin D3 on cholesterol deposition in tissues and conversion into biliary cholesterol and bile acids in young pigs

摘要: Fifty-four crossbred, castrated male pigs with an average initial weight of 10.2 kg were fed diets containing either 1 or 3 times the daily requirement calcium and 1, 5 25 cholecalciferol in a 2 X factorial design. During week 6, fitted femoral artery, coimnon bile duct re-entrant duodenal catheters. Eighteen died during after surgery, giving mortality rate 33%. Causes death included intestinal blockage, euthanasia catheter failure, gastric ulcer, infection surgery. Body at weeks 7 8 greater (P<0.10) than 6 weights, indicating that growing gain from to was for excess recommended amount calcium. Concentrations plasma triacylglycerol decreased (P<0.05) (P<0.10). phospholipid continued decrease (P<0.05). cholesterol but not different between 8. Pigs had concentrations compared LDLand HDL-cholesterol did show significant effects three sampled. less (P<0.01) significantly After 8, collected 48 hours 36 remaining (six per