Incidence Rate of and Factors Associated with Loss to Follow-up in a Longitudinal Cohort of Antiretroviral-Treated HIV-Infected Persons: An AIDS Clinical Trials Group (ACTG) Longitudinal Linked Randomized Trials (ALLRT) Analysis
作者： S. Krishnan , K. Wu , M. Smurzynski , R.J. Bosch , C.A. Benson
DOI: 10.1310/HCT1204-190
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摘要: AbstractPurpose: Examine incidence and factors associated with loss to follow-up (LTFU) in the AIDS Clinical Trials Group (ACTG) Longitudinal Linked Randomized (ALLRT) cohort.Method: ALLRT is a prospective cohort of HIV-infected persons randomized antiretroviral (ARV) regimens/strategies ACTG trials followed long-term after trial ends. Person-years were calculated from entry until (LTFU; defined using off-study reasons or ≥3 consecutive missed visits), death/ severe debilitation/site closures, June 2009 (censored). Poisson regression was used examine LTFU separately among participants who ARV naive experienced at entry.Results: Among 4,630 (22,524 person-years), 1,140 lost follow-up, 237 died, 29 severely debilitated, 443 sites that closed. The 5.5 4.2 per 100 person-years previously ARV-naive ARV-experienced participants, respectively. In both groups, age ≤50...
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