Diabetes in the elderly: Diagnosis, pathogenesis, and therapy

摘要: Abstract The prevalence of diabetes mellitus increases with age; it occurs in approximately 10 percent Americans 60 years age and 16 to 20 those 80 old. Type II is primarily found the elderly, estimated that an additional elderly population has age-associated hyperglycemia, which may be part a spectrum between normality type diabetes. diabetic group at risk for both microvascular macrovascular complications diabetes, whereas hyperglycemia aging macrovascular-type complications. Thus, 40 our senior abnormal carbohydrate tolerance diabetic-type chronic basis state as well probably multifactorial—involving altered insulin secretion action. Unique problems arise treating older patients. Physiologic changes occurring during normal aging, pathologic processes, increased other diseases, polypharmacy must all considered selecting appropriate therapy these A rational approach maintenance glucose homeostasis presented patients