Maintaining the Fully Differentiated Cardiac Sarcomere
作者： Daniel E. Michele , Joseph M. Metzger
DOI: 10.1007/978-1-4612-0199-1_5
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摘要: The contractile proteins of the fully differentiated muscle cell are arranged in a highly ordered three-dimensional lattice. functional interactions among these optimized to produce force and motion response rapid changes intracellular calcium. In sarcomere, structural different complex, some cases forming multimeric complexes (troponin, myosin), micron-long filaments (thick thin filaments), or multicomponent anchoring networks (Z-line). de novo formation sarcomere (myofibrillogenesis) differentiating is very dynamic process, with coordinate regulation protein isoform gene expression, localization newly synthesized myofibrillar structures, organization structures into sarcomeres. process myofibrillogenesis well documented chapters this book has been markedly advanced by recent genetic immunocytochemistry approaches applied embryonic, neonatal, other types cells.
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