Effects of optical isomers of ketamine on excitation of cat and rat spinal neurones by amino acids and acetylcholine.
作者： D. Lodge , N.A. Anis , N.R. Burton
DOI: 10.1016/0304-3940(82)90330-5
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摘要: Abstract The (+) isomer of ketamine was approximately 3 and 1.5 times as potent the (−) in reducing excitation rat cat Renshaw cells by N-methylaspartate (NMA) acetylcholine (ACh) respectively. potency ratio two isomers NMA antagonists similar to that obtained anaesthetic analgesic tests [16, 19, 25].
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