Characterisation of a high-molecular-weight developmentally regulated adult rat liver-specific protein
作者： Usha K. Srinivas , C.J. Revathi
DOI: 10.1016/0167-4838(92)90215-Y
关键词:
摘要: A major, hitherto unknown protein which is shown to be developmentally regulated has been isolated from rat liver. The a molecular mass of 150 kDa and constitutes 8-10% the adult liver protein. Immunoblot experiments immunofluorescence studies established its presence specifically in cells. This not present early embryonic cells, gets induced around day 18 gestation reaches near levels by 1 after birth found cells an ascitic hepatoma. Unlike albumin alpha-fetoprotein, two well known proteins, secreted. Some characteristics this liver-specific are discussed.
elsevier.com
sci-hub.se 参考文章(9)
Carl C. Kuhn, John W. Crabb, Modern Manual Microsequencing Methods Springer, Berlin, Heidelberg. pp. 64- 76 ,(1986) , 10.1007/978-3-642-71534-1_7
S Clarke, A major polypeptide component of rat liver mitochondria: carbamyl phosphate synthetase. Journal of Biological Chemistry. ,vol. 251, pp. 950- 961 ,(1976) , 10.1016/S0021-9258(17)33785-7
John Papaconstantinou, Jeffrey P. Rabek, Dong-Er Zhang, Molecular mechnisms of liver-specific albumin and α-fetoprotein gene regulation: A review Development Growth & Differentiation. ,vol. 32, pp. 205- 216 ,(1990) , 10.1111/J.1440-169X.1990.00205.X
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
N HASTIE, The expression of three abundance classes of messenger RNA in mouse tissues Cell. ,vol. 9, pp. 761- 774 ,(1976) , 10.1016/0092-8674(76)90139-2
Carole H. Sellem, Monique Frain, Tamas Erdos, JoséM. Sala-Trepat, Differential expression of albumin and α-fetoprotein genes in fetal tissues of mouse and rat Developmental Biology. ,vol. 102, pp. 51- 60 ,(1984) , 10.1016/0012-1606(84)90174-X
U. K. LAEMMLI, Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 Nature. ,vol. 227, pp. 680- 685 ,(1970) , 10.1038/227680A0
U K Srinivas, C J Revathi, M R Das, Heat-induced expression of albumin during early stages of rat embryo development. Molecular and Cellular Biology. ,vol. 7, pp. 4599- 4602 ,(1987) , 10.1128/MCB.7.12.4599
Michael W. Hunkapiller, Eva Lujan, Frank Ostrander, Leroy E. Hood, [17] Isolation of microgram quantities of proteins from polyacrylamide gels for amino acid sequence analysis Enzyme Structure Part I. ,vol. 91, pp. 227- 236 ,(1983) , 10.1016/S0076-6879(83)91019-4