Intraocular lenses, bacterial adhesion and endophthalmitis prevention: a review.

摘要: Postoperative endophthalmitis following intraocular lens (IOL) implantation is still one of the most feared complications cataract surgery. Bacterial adhesion to IOLs during their insertion a prominent etiological factor. Polypropylene was first biomaterial that allowed this relation cause and effect be proven. Following adhesion, bacteria replicate, congregate form multiple layers microcolonies which actually represent basic structural unit biofilm. The are embedded in slime layer. Personal photographs illustrate different steps biofilm formation. This matrix not only an adhesive medium; it also affects virulence. Adhesion has been studied by several vitro studies discrepancies can found between them due variations experimental conditions. strains, incubation times methods all varied. affected nature IOLs, isolates surrounding medium. Since medium very difficult model because its complexity, vivo seemed essential. We have recently determined evolution amount attached five types IOLs. Crystalline lenses from 90 domestic pigs were removed aseptically replaced with previously infected There few epidemiological published determine relationship IOL type. However, perfect could prevent postoperative does yet exist. Globally, hydrophilic materials hydrophobic acrylic seem less sticky than silicone or PMMA, but remains proven clinically.