Marginal metallophilic cells of the mouse spleen identified by a monoclonal antibody.

摘要: A monoclonal antibody, MOMA-1, is described that recognizes the marginal metallophilic macrophages in mouse spleen. The cells are localized at sinus forming a ring around periarteriolar lymphocyte sheath and follicular areas inner side of zone. They show high non-specific esterase activity can be distinguished from zone by antibody staining lack FITC-Ficoll uptake. relationship MOMA-1-positive with other macrophage populations discussed.