Method for reducing nitro of Fingolimod intermediate to amino

摘要: The invention discloses a method for reducing nitro of Fingolimod intermediate to amino. comprises the following steps: firstly, carrying out reaction on and ammonium formate in presence palladium catalyst solvent; then, acidizing with hydrochloric acid form salt. adopts combining replace use high pressure kettle hydrogen or an active hydrogenation agent conventional reduction process, so as overcome deficiencies which are disadvantageous industrialized production such relatively control demand, low safety coefficient, difficult operation. provides novel has advantages mild condition, simplicity operation, rate, cost saving, environment friendliness like, is simple operate easy industrially produce.