Staphylococcus aureus nasal carriage in patients on haemodialysis: role of cutaneous colonization
作者： C. Peña , N. Fernández-Sabe , M.A. Domı́nguez , M. Pujol , A. Martinez-Castelao
DOI: 10.1016/J.JHIN.2004.04.018
关键词:
摘要: We performed a prospective study of Staphylococcus aureus nasal carriage in patients on chronic haemodialysis to determine the role cutaneous colonization aetiology recurrent colonization. From February 2000 September 2001, 71 dialysis unit at university hospital were screened monthly for S. carriage. Carriers received mupirocin five days and tested two later thereafter. Using genotyping results, recurrence was defined as relapse if pretreatment subsequent isolates clonally identical; different, it considered recolonization. Thirty-nine (55%) carriers: 11 initially 28 during follow-up. Among mupirocin-treated patients, eradication rate 88.5%. Nasal documented 17 (43.5%), strains available molecular typing 14 with total 23 episodes. On basis pulsed-field gel electrophoresis analysis, 16 (70%) episodes relapses seven (30%) recolonizations. relapse, prior detected only three cases. In majority recurrences after therapy due relapses. Cutaneous does not appear be relevant development these
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