Venous thromboembolism in pregnancy and the puerperium: incidence and additional risk factors from a London perinatal database

摘要: Objective To determine the incidence of venous thromboembolism in pregnancy and puerperium to identify risk factors for pregnancy-related thromboembolism. Design Cohort study case–control study. Setting London, UK. Population 395,335 women with live births or pregnancies 24 more weeks gestation between 1988 1997. Methods Data extraction from St Mary's Maternity Information System database. Random sample 5% study. Main outcome measures Incidence thromboembolism; odds ratios variables associated thromboembolism. Results The was 85/100,000 maternities. There were approximately twice as many postpartum antepartum events. Blood group A, multiple pregnancy, caesarean section, cardiac disease, delivery at gestational age <36 weeks, a body mass index ≥25, maternal 35 over all found increase thromboembolism. Conclusions Although is leading cause deaths UK, it still rare event. Most these events are deep vein thromboses occurring period. Antenatally birth an important factor. Postnatally who have had premature history disease should be assessed carefully thromboembolism.