Immunity of cholera in man: Relative role of antibacterial versus antitoxic immunity

作者: Myron M. Levine , David R. Nalin , John P. Craig , David Hoover , Eric J. Bergquist

DOI: 10.1016/0035-9203(79)90119-6

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摘要: Purified cholera toxoid is antigenic when given enterally and orally. fails to provide protection against experimental challenge. Clinical confers formidable homologous or heterologous rechallenge. Failure culture vibrios from intestinal fluid stool of re-challenge volunteers suggests that the predominant immune mechanism antibacterial rather than antitoxic.

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