作者: Myron M. Levine , David R. Nalin , John P. Craig , David Hoover , Eric J. Bergquist
DOI: 10.1016/0035-9203(79)90119-6
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摘要: Purified cholera toxoid is antigenic when given enterally and orally. fails to provide protection against experimental challenge. Clinical confers formidable homologous or heterologous rechallenge. Failure culture vibrios from intestinal fluid stool of re-challenge volunteers suggests that the predominant immune mechanism antibacterial rather than antitoxic.