Acetone-butanol fermentation and its variants

摘要: Recent intensive research on the acetone-butanol-ethanol and isopropanol-butanol-ethanol fermentation has increased basic understanding of these processes substantially. Metabolic investigations Clostridium acetobutylicum, beijerinkii show that enzyme activities necessary for solvent production are induced only in solvent-producing cells. Although produced, or added, acetic butyric acid have significant effects metabolic activities, transition from to cannot as yet be fully explained. Based studies continuous cultures, kinetics product formation can described. Knowledge mechanism butanol toxicity is accumulating but no dramatic increase tolerance so far been obtained. Successful results, approaching limitations determined by biological technological possibilities, obtained batch based immobilized Continuous superior cultures respect their productivity.