Chronic fatigue syndrome and mitochondrial dysfunction

摘要: This study aims to improve the health of patients suffering from chronic fatigue syndrome (CFS) by interventions based on biochemistry illness, specifically function mitochondria in producing ATP (adenosine triphosphate), energy currency for all body functions, and recycling ADP diphosphate) replenish supply as needed. Patients attending a private medical practice specializing CFS were diagnosed using Centers Disease Control criteria. In consultation with each patient, an integer Bell Ability Scale was assigned, blood sample taken “ATP profile” test, designed other conditions. Each test produced 5 numerical factors which describe availability neutrophils, fraction complexed magnesium, efficiency oxidative phosphorylation, transfer efficiencies into cytosol where is used. With consent 71 53 normal, healthy controls have been collated compared Scale. The individual show that different combinations biochemical lesions. When are combined, remarkable correlation observed between degree mitochondrial dysfunction severity illness (P<0.001). Only 1 overlaps normal region. powerful diagnostic tool can differentiate who symptoms result wastage stress psychological those insufficient due cellular respiration dysfunction. indicate remedial actions, form dietary supplements, drugs detoxification, most likely be benefit, what further tests should carried out.