Noise-Induced Cochlear Synaptopathy and Ribbon Synapse Regeneration: Repair Process and Therapeutic Target.
作者： Jian Wang , Shankai Yin , Hengchao Chen , Lijuan Shi
DOI: 10.1007/978-981-13-6123-4_3
关键词:
摘要: The synapse between the inner hair cells (IHCs) and spiral ganglion neurons (SGNs) in mammalian cochleae is characterized as having presynaptic ribbons therefore called ribbon synapse. special molecular organization reviewed this chapter association with functional feature of signal processing. This followed by review on noise-induced damage to a focus recent reports animal models which effect brief noise exposures observed without causing significant permanent threshold shift (PTS). In regard, potential mechanism synaptic impact hearing are summarized clarify concept hidden loss, defined deficits elevation. A controversial issue addressed whether disrupted synapses can be regenerated. Moreover, summarizes work therapeutic research protect or promote regeneration after initial disruption. Lastly, several unresolved issues raised for investigation future.
springer.com
sci-hub.se 参考文章(114)
V. VYKLICKY, M. KORINEK, T. SMEJKALOVA, A. BALIK, B. KRAUSOVA, M. KANIAKOVA, K. LICHNEROVA, J. CERNY, J. KRUSEK, I. DITTERT, M. HORAK, L. VYKLICKY, Structure, Function, and Pharmacology of NMDA Receptor Channels Physiological Research. ,vol. 63, ,(2014) , 10.33549/PHYSIOLRES.932678
J L Puel, Cochlear NMDA receptor blockade prevents salicylate-induced tinnitus. B-ent. pp. 19- 22 ,(2007)
P. Shen, L. Liu, S. Tao, X. Li, Q. Song, Z. Yu, S. Yin, J. Wang, L. Shi, X. Guo, Noise-induced damage to ribbon synapses without permanent threshold shifts in neonatal mice. Neuroscience. ,vol. 304, pp. 368- 377 ,(2015) , 10.1016/J.NEUROSCIENCE.2015.07.066
Carmen Valente, Stefania Spanò, Alberto Luini, Daniela Corda, Purification and functional properties of the membrane fissioning protein CtBP3/BARS. Methods in Enzymology. ,vol. 404, pp. 296- 316 ,(2005) , 10.1016/S0076-6879(05)04027-9
M A Adly, L Vollrath, I Spiwoks-Becker, Ultrastructural changes of photoreceptor synaptic ribbons in relation to time of day and illumination Investigative Ophthalmology & Visual Science. ,vol. 40, pp. 2165- 2172 ,(1999)
J.-L. Puel, J. Ruel, M. Guitton, R. Pujol, The inner hair cell afferent/efferent synapses revisited: a basis for new therapeutic strategies. Advances in oto-rhino-laryngology. ,vol. 59, pp. 124- 130 ,(2002) , 10.1159/000059250
Bernd Fritzsch, Lino Tessarollo, Enzo Coppola, Louis F. Reichardt, Neurotrophins in the ear: their roles in sensory neuron survival and fiber guidance Progress in Brain Research. ,vol. 146, pp. 265- 278 ,(2004) , 10.1016/S0079-6123(03)46017-2
Dan Bing, Sze Chim Lee, Dario Campanelli, Hao Xiong, Masahiro Matsumoto, Rama Panford-Walsh, Stephan Wolpert, Mark Praetorius, Ulrike Zimmermann, Hanqi Chu, Marlies Knipper, Lukas Rüttiger, Wibke Singer, Cochlear NMDA receptors as a therapeutic target of noise-induced tinnitus. Cellular Physiology and Biochemistry. ,vol. 35, pp. 1905- 1923 ,(2015) , 10.1159/000374000
Lin Shi, Ke Liu, Haolin Wang, Yue Zhang, Zhijun Hong, Mingyu Wang, Xiaoyu Wang, Xuejun Jiang, Shiming Yang, Noise induced reversible changes of cochlear ribbon synapses contribute to temporary hearing loss in mice Acta Oto-laryngologica. ,vol. 135, pp. 1093- 1102 ,(2015) , 10.3109/00016489.2015.1061699
Howard Prentice, Jigar Pravinchandra Modi, Jang-Yen Wu, None, Mechanisms of Neuronal Protection against Excitotoxicity, Endoplasmic Reticulum Stress, and Mitochondrial Dysfunction in Stroke and Neurodegenerative Diseases Oxidative Medicine and Cellular Longevity. ,vol. 2015, pp. 964518- 964518 ,(2015) , 10.1155/2015/964518