Micronutrient and Amino Acid Losses During Renal Replacement Therapy for Acute Kidney Injury.
作者： Weng C. Oh , Bruno Mafrici , Mark Rigby , Daniel Harvey , Andrew Sharman
DOI: 10.1016/J.EKIR.2019.05.001
关键词:
摘要: Introduction Malnutrition is common in patients with acute kidney injury (AKI), particularly those requiring renal replacement therapy (RRT). Use of RRT removes metabolic waste products and toxins, but it will inevitably also remove useful molecules such as micronutrients, which might aggravate malnutrition. The modalities vary mechanism solute removal; for example, intermittent hemodialysis (IHD) uses diffusion, continuous veno-venous hemofiltration (CVVH) convection, sustained low-efficiency diafiltration (SLEDf) a combination these. Methods We assessed micronutrient amino acid losses 3 different AKI (IHD, n = 27; SLEDf, 12; CVVH, 21) after correction dialysis dose plasma concentrations. Results Total were affected by modality; generally CVVH >> SLEDf > IHD (e.g., loss was 18.69 ± 3.04, 8.21 4.07, 5.13 3.1 g, respectively; P Conclusion Micronutrient are marked during AKI, variation between micronutrients.
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