The economic burden and symptom manifestations of chronic rhinosinusitis.

摘要: BACKGROUND The aim of this study was to delineate patient symptoms and economic burdens chronic rhinosinusitis (CRS). METHODS Adult patients with CRS were assessed prospectively a survey instrument. Symptom scores for major minor CRS, medication use, physician visits work days missed determined. Cost analyses conducted. RESULTS Three hundred twenty-two studied (mean age, 42.3 years). Nasal obstruction facial congestion the most common severe symptoms, headache fatigue symptoms. Patients received an average 2.7 antibiotic courses used nasal steroids prescription antihistamines 18.3 16.3 weeks, respectively, in 12-month period. Mean medical resource costs 921 dollars per patient-year. caused 4.8 overall yearly cost 1539 patient. CONCLUSION prevail over systemic oropharyngeal CRS. Significant expenditures global accompany