Operative and Survival Outcomes with Selective Neo-adjuvant Radiotherapy and Conventional Abdomino-Perineal Resection

摘要: Aims: Low rectal cancer treated with abdomino-perineal resection (APR) compared anterior has been shown to have higher rates of local recurrence (LR). It is thought that changes in surgical technique can improve outcomes and increasingly radical operations for tumours not amenable restoration bowel continuity are now being practiced. We investigated factors influencing patients undergoing APR our institution. Methods: Consecutive who underwent adenocarcinoma between August 2000 2005 a large single centre were retrospectively analysed, minimum follow up 60 months. Results: 68 APR, mean age was 65 years. Pre-operative radiotherapy given 29 (43%) patients. There 2.9% in-hospital mortality (n=2). 20.6% (n=14) had circumferential margin (CRM) ?1mm. 4 intra-operative perforations (5.9%). Overall there 7.3% LR rate (n=5). 1.9% amongst the CRM -ve group (1/54) 28.6% +ve (4/14). Conclusions: Our historical results operative using conventional do replicate very high incomplete tumour perforation described some reports. series demonstrates link positivity particularly advanced tumours. Radiotherapy may prevent those sub-optimal surgery.