Transluminal implantation of artificial heart valves. Description of a new expandable aortic valve and initial results with implantation by catheter technique in closed chest pigs.

摘要: A new artificial aortic valve prosthesis was developed for implantation by the transluminal catheter technique without thoracotomy or extracorporal circulation. The heart prepared mounting a porcine into an expandable stent. Before implantation, stent-valve mounted on balloon and compressed around deflated balloon. then advanced retrogradely to ascending aorta root in anaesthetized pigs. Implantation performed inflation which expanded diameter exceeding internal of vesselemdash thus ensuring stable fixation against vessel wall. total nine implantations were seven 70 kg closed chest Sub- supracoronary two three pigs, respectively, while both positions done two. Angiographic haemodynamic evaluation after revealed no significant stenosis (< 16 mmHg) any valves trivial regurgi-tation only Complications associated with restriction coronary blood flow animals. This preliminary study indicates that can be implanted animals technique.