Company profile: BluePen Biomarkers LLC – integrated biomarker solutions.
作者： Ian A Blair , Clementina Mesaros , Patrick Lilley , Matthew Nunez
关键词:
摘要: BluePen Biomarkers provides a unique comprehensive multi-omics biomarker discovery and validation platform. We can quantify, integrate analyze genomics, proteomics, metabolomics lipidomics biomarkers, alongside clinical data, demographics other phenotypic data. A bio-inspired signal processing analytic approach is used that has the proven ability to identify biomarkers in wide variety of diseases. The resulting be for diagnosis, prognosis, mechanistic studies predicting treatment response, contexts from core research through trials. an additional groundbreaking goal: identifying surrogate different modalities. This not only new biological insights, but enables least invasive, least-cost tests meet or exceed predictive quality current tests.
future-science.com
sci-hub.se 参考文章(18)
Andrew J Worth, Sankha S Basu, Eric C Deutsch, Wei-Ting Hwang, Nathaniel W Snyder, David R Lynch, Ian A Blair, Stable isotopes and LC–MS for monitoring metabolic disturbances in Friedreich's ataxia platelets Bioanalysis. ,vol. 7, pp. 1843- 1855 ,(2015) , 10.4155/BIO.15.118
Surendra Bansal, Anthony DeStefano, Key elements of bioanalytical method validation for small molecules. Aaps Journal. ,vol. 9, ,(2007) , 10.1208/AAPSJ0901011
Clementina Mesaros, Jasbir S. Arora, Ashley Wholer, Anil Vachani, Ian A. Blair, 8-Oxo-2'-deoxyguanosine as a biomarker of tobacco-smoking-induced oxidative stress. Free Radical Biology and Medicine. ,vol. 53, pp. 610- 617 ,(2012) , 10.1016/J.FREERADBIOMED.2012.04.006
George Poste, Bring on the biomarkers Nature. ,vol. 469, pp. 156- 157 ,(2011) , 10.1038/469156A
Yuan Yan, Valerie M. Weaver, Ian A. Blair, Analysis of protein expression during oxidative stress in breast epithelial cells using a stable isotope labeled proteome internal standard. Journal of Proteome Research. ,vol. 4, pp. 2007- 2014 ,(2005) , 10.1021/PR050175D
Angela Y. Wehr, Emma E. Furth, Vineet Sangar, Ian A. Blair, Kenneth H. Yu, Analysis of the Human Pancreatic Stellate Cell Secreted Proteome Pancreas. ,vol. 40, pp. 557- 566 ,(2011) , 10.1097/MPA.0B013E318214EFAF
Sumit J. Shah, Kenneth H. Yu, Vineet Sangar, Samuel I. Parry, Ian A. Blair, Identification and quantification of preterm birth biomarkers in human cervicovaginal fluid by liquid chromatography/tandem mass spectrometry. Journal of Proteome Research. ,vol. 8, pp. 2407- 2417 ,(2009) , 10.1021/PR8010342
Angela Y. Wehr, Wei-Ting Hwang, Ian A. Blair, Kenneth H. Yu, Relative Quantification of Serum Proteins from Pancreatic Ductal Adenocarcinoma Patients by Stable Isotope Dilution Liquid Chromatography–Mass Spectrometry Journal of Proteome Research. ,vol. 11, pp. 1749- 1758 ,(2012) , 10.1021/PR201011F
Sankha S Basu, Ian A Blair, SILEC: a protocol for generating and using isotopically labeled coenzyme A mass spectrometry standards. Nature Protocols. ,vol. 7, pp. 1- 12 ,(2012) , 10.1038/NPROT.2011.421
Sankha S. Basu, Clementina Mesaros, Stacy L. Gelhaus, Ian A. Blair, Stable Isotope Labeling by Essential Nutrients in Cell Culture for Preparation of Labeled Coenzyme A and Its Thioesters Analytical Chemistry. ,vol. 83, pp. 1363- 1369 ,(2011) , 10.1021/AC1027353