Comparison of two methods of reconstruction for primary malignant tumors at the knee: a sequential cohort study.

摘要: Background and Objectives The purpose of this study was to compare the complications functional outcome associated with use an irradiated allograft-implant composite or a bone-ingrowth modular tumor prosthesis for replacement knee joint after resection bone sarcoma from distal femur proximal tibia. Methods Eleven patients initially received allograft reconstruction, followed by 64 treated prosthesis. The primary analysis concerned reconstructive failure, defined requirement removal original construct. Functional assessed using 1987 Musculoskeletal Tumor Society rating system. Results Reconstructive failure occurred in 6 11 (55%) constructs compared 10 (16%) prostheses (P = 0.009). Failures were due infection (2 allografts versus 4 prostheses; P = 0.2) mechanical (4 fractures 5 broken prosthetic stems 1 aseptically loose prosthesis; P = 0.03). limb salvage rate 95% (61 64) 64% (7 11) those (P = 0.007). Patients had better mean score 75% 57% reconstruction (P = 0.006). Conclusions This comparative suggests that surgery at has more predictable than reconstruction. J. Surg. Oncol. 2001; 77:89–99. © 2001 Wiley-Liss, Inc.