摘要: Herpes simplex virus (herpesvirus) was isolated from autopsy lung specimens of 20 patients with clinical, roentgenographic, and histologic evidence pneumonia. Mucocutaneous herpesvirus infection preceded the onset pneumonia in 17. Twelve had focal pneumonia, 10 whom concomitant herpetic tracheitis, esophagitis, or both. Eight diffuse interstitial six dissemination to other organs. Of eight isolates available for typing, seven were herpesvirus-1 one, herpesvirus-2. A high prevalence antibody serum samples obtained before identical restriction endonuclease patterns between mucosal individual indicated that, most cases, due endogenous reactivation virus. Focal appeared result contiguous spread parenchyma, whereas be a manifestation hematogenous
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