From epithelial remodelling to carcinogenesis.
作者： Leszek Satora , Jennifer Mytych , Anna Bilska-Kos , Katarzyna Kozioł
DOI: 10.1016/J.PBIOMOLBIO.2019.08.001
关键词:
摘要: Abstract The novel cancer theory named ‘the tissue organization field theory’ (TOFT) suggests that carcinogenesis is a process analogous to embryonic development, whereby organs are formed through interactions among different cell types. suggested ‘morphological remodelling’ of the epithelium under hypoxia in gut breathing fish (GBF) has many common features with carcinogenesis. It appears research into relationship epidermal growth factor receptor (EGFR), inducible (HIF) as well and normoxia states GBF fishes can be crucial learning about steering mechanisms squamous proliferation, leading better understanding
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