Directed evolution of carbon-hydrogen bond activating enzymes.
作者： Raphael Frey , Takahiro Hayashi , Rebecca M Buller
DOI: 10.1016/J.COPBIO.2018.12.004
关键词:
摘要: … of more sophisticated learning algorithms for the directed evolution and, ultimately, the … The authors used combination of error-prone PCR and site directed mutagenesis to evolve 7…
sci-hub.se 参考文章(83)
Martina Quintanar-Audelo, Yong Koy Bong, Derek Smith, Haibin Chen, Anupam Gohel, Steven J. Collier, Hong Yang, Fabien Cabirol, Tao Li, Jeffrey C. Moore, Biocatalysts and methods for hydroxylation of chemical compounds ,(2013)
Jovana Nazor, Derek Smith, Ernst Kuesters, Shiwei Song, Michael Crowe, Thomas Ruch, Dominique Grimler, Michael Foulkes, Shangjun Teng, Changxue Lin, Yunzhong Li, Giancarlo Francese, Kurt Laumen, Chemical process for preparing spiroindolones and intermediates thereof ,(2013)
Salette Martinez, Robert P. Hausinger, Catalytic Mechanisms of Fe(II)- and 2-Oxoglutarate-dependent Oxygenases Journal of Biological Chemistry. ,vol. 290, pp. 20702- 20711 ,(2015) , 10.1074/JBC.R115.648691
Kento Koketsu, Yasuhito Shomura, Kei Moriwaki, Mikiro Hayashi, Satoshi Mitsuhashi, Ryotaro Hara, Kuniki Kino, Yoshiki Higuchi, Refined regio- and stereoselective hydroxylation of L-pipecolic acid by protein engineering of L-proline cis-4-hydroxylase based on the X-ray crystal structure. ACS Synthetic Biology. ,vol. 4, pp. 383- 392 ,(2015) , 10.1021/SB500247A
Fu-She Han, Transition-metal-catalyzed Suzuki-Miyaura cross-coupling reactions: a remarkable advance from palladium to nickel catalysts Chemical Society Reviews. ,vol. 42, pp. 5270- 5298 ,(2013) , 10.1039/C3CS35521G
U. T. Bornscheuer, G. W. Huisman, R. J. Kazlauskas, S. Lutz, J. C. Moore, K. Robins, Engineering the third wave of biocatalysis Nature. ,vol. 485, pp. 185- 194 ,(2012) , 10.1038/NATURE11117
C. K. Savile, J. M. Janey, E. C. Mundorff, J. C. Moore, S. Tam, W. R. Jarvis, J. C. Colbeck, A. Krebber, F. J. Fleitz, J. Brands, P. N. Devine, G. W. Huisman, G. J. Hughes, Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture Science. ,vol. 329, pp. 305- 309 ,(2010) , 10.1126/SCIENCE.1188934
Jared C. Lewis, Frances H. Arnold, Catalysts on Demand: Selective Oxidations by Laboratory-Evolved Cytochrome P450 BM3 Chimia. ,vol. 63, pp. 309- 312 ,(2009) , 10.2533/CHIMIA.2009.309
Christopher C. Farwell, Ruijie K. Zhang, John A. McIntosh, Todd K. Hyster, Frances H. Arnold, Enantioselective Enzyme-Catalyzed Aziridination Enabled by Active- Site Evolution of a Cytochrome P450 ACS central science. ,vol. 1, pp. 89- 93 ,(2015) , 10.1021/ACSCENTSCI.5B00056
Priska Le-Huu, Tanja Heidt, Birgit Claasen, Sabine Laschat, Vlada B. Urlacher, Chemo-, Regio-, and Stereoselective Oxidation of the Monocyclic Diterpenoid β-Cembrenediol by P450 BM3 ACS Catalysis. ,vol. 5, pp. 1772- 1780 ,(2015) , 10.1021/CS5020404