Risk factors associated with necrotising enterocolitis in very low birth weight infants in Malaysian neonatal intensive care units.

摘要: INTRODUCTION This study aimed to identify the risk factors associated with necrotising enterocolitis (NEC) in very low birth weight (VLBW; < 1,501 g) infants Malaysian neonatal intensive care units (NICUs). METHODS was a retrospective based on data collected standardised format for all VLBW born 2007 (n = 3,601) and admitted 31 NICUs public hospitals. A diagnosis of NEC made clinical, radiological and/or histopathological evidence stage II or III, according Bell's criteria. Logistic regression analysis performed determine significant NEC. RESULTS 222 (6.2%) developed (stage II, n 197; 25). 69 (31.3%) died 58; 11). The were: maternal age (adjusted odds ratio [OR] 1.024, 95% confidence interval [CI] 1.003-1.046; p 0.027), intrapartum antibiotics (OR 0.639, CI 0.421-0.971; 0.036), 0.999, 0.998-0.999; 0.001), surfactant therapy 1.590, 1.170-2.161; 0.003), congenital pneumonia 2.00, 1.405-2.848; 0.001) indomethacin closure patent ductus arteriosus (PDA) 1.821, 1.349-2.431; 0.001). CONCLUSION Increasing age, decreasing weight, therapy, PDA were an increased infants. Infants that received reduced developing