Rotavirus-related Hospitalizations Are Responsible for High Seasonal Peaks in All-cause Pediatric Hospitalizations

摘要: BACKGROUND: Seasonal rotavirus (RV) epidemics partly overlap with those of other common childhood infections, thereby generating enormous, but poorly quantified, pressure on hospital resources during winter and spring. We assessed RV contribution to seasonal excess in all-cause pediatric hospitalizations hospitalization incidence rate an observational study. METHODS: The study was conducted among wards 3 general hospitals 1 tertiary care center. Numbers were determined from 5-year data confirmed adjusted for underreporting, through active surveillance acute gastroenteritis the 2011 season. Incidence administrative population statistics. RESULTS: accounted 6.2% (95% confidence interval: 5.3-7.1) 3.1% 2.9-3.3) at center, proportion underreporting patients (33%) as observed surveillance. Among hospitals, there a 30% increase season infections compared summer months. contributed 31% hospitalizations, representing 12.9% between January May. 510/100,000 child-years <5 years 420-600). CONCLUSION: is one main causes peaks such contributes significantly periodic high bed capacity pressures associated adverse effects. vaccination benefits this respect should be considered decision-making processes.