Dopamine Depresses Synaptic Inputs Into the Olfactory Bulb
作者： Albert Y. Hsia , Jean-Didier Vincent , Pierre-Marie Lledo
DOI: 10.1152/JN.1999.82.2.1082
关键词:
摘要: Both observations in humans with disorders of dopaminergic transmission and molecular studies point to an important role for dopamine olfaction. In this study we found that receptor activation the olfactory bulb causes a significant depression synaptic at first relay between neurons mitral cells. This was be caused by D2 subtype reversible specific antagonist. A change paired-pulse modulation during suggests presynaptic locus action. The occur independent activity. These results provide evidence control inputs main bulb. magnitude dopamine’s modulatory capabilities suggest roles odorant processing.
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