Deguelin as a chemopreventive agent for lung cancer

摘要: The present invention provides the chemopreventive agent deguelin, a natural product isolated from Mundulea serica (Leguminosae), and derivatives thereof, for use in combination with second inhibiting growth premalignant malignant lung cancer cells by causing G2/M arrest apoptosis. Thus, deguelin-based therapies treatment prevention of cancer. may, particular, be an inhibitor P13K, MAPK or JNK signaling pathways, chemotherapeutic agent, radiotherapeutic agent.